Rotate tapes for full backups?

We don't have a ton of data, a full backup covers about 6 800gb tapes, but we don't have a way to replicate this data off site so its safe (disaster recovery wise).

I have thought about removing the tapes involved in the full backup and then putting NEW tapes in their place for the next run of the full backup.  Is there anythign special I need to do in Backup Exec to remove these tapes and not cause a problem in the system if I need to reinsert them into the backup drive for recovery????

Or is it just a process of removing the tapes in question, and inserting new tapes into those empty slots???