Optimised Dedupe over dedicated network

I'm currently backing up servers over a production network and running optimised dedupe to a remote site for offsite backups (with Backup Exec 2012)

This is running over a production WAN but I have another replication network available - is it possible to force the optimised dedupe traffic over another network.

The agents cannot see this replication network, so the backup exec servers would need to still run backups over the production network and just use a separate network for the replication traffic.

Thanks, Davod